Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564171 | 0.91 | ALDH1A1 (0.39) | ALDH1A1LMNAKDM4EKMT2AMAPK8 | |
| SCHEMBL22563864 | 0.89 | TSHR (0.39) | ALDH1A1LMNAKMT2AMRGPRX4NPSR1 | |
| SCHEMBL22564036 | 0.88 | NPC1 (0.34) | ALDH1A1LMNAKDM4EKMT2ANPSR1 | |
| SCHEMBL22564198 | 0.88 | ALDH1A1 (0.36) | ALDH1A1LMNAKDM4EKMT2AMAPK8 | |
| SCHEMBL18500404 | 0.88 | ALDH1A1 (0.35) | ALDH1A1LMNAKDM4EKMT2AMAPK8 | |
| SCHEMBL22563845 | 0.87 | FOLH1 (0.34) | ALDH1A1MRGPRX4HTTTP53 | |
| SCHEMBL22564032 | 0.87 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EKMT2ATP53 | |
| SCHEMBL22564378 | 0.87 | PDE5A (0.31) | — | |
| SCHEMBL22564506 | 0.86 | MEN1 (0.35) | KMT2AMEN1 | |
| SCHEMBL22563884 | 0.86 | FOLH1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |