Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564296 | 0.92 | TSHR (0.41) | TSHRJMJD6GABRA5MRGPRX4ALDH1A1 | |
| SCHEMBL22564032 | 0.92 | ALDH1A1 (0.41) | TSHRJMJD6ALDH1A1HSD17B10LMNA | |
| SCHEMBL22564298 | 0.89 | TSHR (0.39) | TSHRJMJD6GABRA5MRGPRX4ALDH1A1 | |
| SCHEMBL22563909 | 0.89 | ALDH1A1 (0.34) | MRGPRX4ALDH1A1LMNATDP1TP53 | |
| SCHEMBL18504279 | 0.88 | TSHR (0.40) | TSHRJMJD6GABRA5MRGPRX4ALDH1A1 | |
| SCHEMBL22563850 | 0.87 | JMJD6 (0.44) | TSHRJMJD6GABRA5ALDH1A1LMNA | |
| SCHEMBL22564101 | 0.87 | TSHR (0.42) | TSHRJMJD6GABRA5ALDH1A1HSD17B10 | |
| SCHEMBL22564036 | 0.86 | NPC1 (0.34) | TSHRJMJD6GABRA5ALDH1A1HSD17B10 | |
| SCHEMBL22564497 | 0.86 | TBXAS1 (0.39) | TSHRJMJD6GABRA5ALDH1A1HSD17B10 | |
| SCHEMBL22563845 | 0.85 | FOLH1 (0.34) | MRGPRX4ALDH1A1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |