SCHEMBL22563945

SCHEMBL22563945

O=C(Br)c1cccc(SC(F)(F)F)c1COc1ccn(S)n1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 9/20 0.33
FFAR1 O14842 4/20 0.33
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564285 0.90 FFAR4 (0.36) FFAR4FFAR1HCRTR1HCRTR2
SCHEMBL22563983 0.90 RXFP1 (0.32) FFAR4FFAR1
SCHEMBL22564384 0.89 FFAR4 (0.33) FFAR4FFAR1HCRTR1HCRTR2
SCHEMBL22564314 0.89 FFAR4 (0.33) FFAR4FFAR1HCRTR1HCRTR2
SCHEMBL18505002 0.88 FFAR4 (0.34) FFAR4FFAR1HCRTR1HCRTR2
SCHEMBL22564400 0.88 FFAR4 (0.32) FFAR4FFAR1
SCHEMBL22564473 0.88 POLB (0.34) FFAR4HCRTR1HCRTR2
SCHEMBL22564275 0.87 FFAR4 (0.32) FFAR4FFAR1
SCHEMBL22564371 0.86
SCHEMBL22564267 0.86 L3MBTL1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed