SCHEMBL22563983

SCHEMBL22563983

O=C(NBr)c1cccc(SC(F)(F)F)c1COc1ccn(S)n1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 2/20 0.32
FFAR4 Q5NUL3 3/20 0.32
KCNK2 O95069 1/20 0.31
KCNK10 P57789 1/20 0.31
FFAR1 O14842 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564400 0.92 FFAR4 (0.32) RXFP1FFAR4FFAR1
SCHEMBL22564275 0.91 FFAR4 (0.32) RXFP1FFAR4FFAR1
SCHEMBL22563945 0.90 FFAR4 (0.33) FFAR4FFAR1
SCHEMBL18504863 0.89 RXFP1 (0.33) RXFP1FFAR4KCNK2KCNK10FFAR1
SCHEMBL22564285 0.89 FFAR4 (0.36) FFAR4KCNK2KCNK10FFAR1
SCHEMBL22564473 0.88 POLB (0.34) FFAR4
SCHEMBL22564314 0.88 FFAR4 (0.33) FFAR4FFAR1
SCHEMBL22564384 0.88 FFAR4 (0.33) FFAR4FFAR1
SCHEMBL22564174 0.87
SCHEMBL22564158 0.86 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed