SCHEMBL22563977

SCHEMBL22563977

CN(N)C(=O)N(N)c1cccc(OC(F)(F)F)c1I

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 1/20 0.34
KCNK3 O14649 4/20 0.34
KCNK9 Q9NPC2 4/20 0.34
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
SCN9A Q15858 5/20 0.33
GAA P10253 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
RXFP1 Q9HBX9 1/20 0.31
F2R P25116 1/20 0.31
HCRTR1 O43613 1/20 0.31
HCRTR2 O43614 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22564438 0.83 CA12 (0.39) ALDH1A1
SCHEMBL22590945 0.82 KCNK3 (0.33) GPBAR1KCNK3KCNK9ALDH1A1L3MBTL1
SCHEMBL22564232 0.81 L3MBTL1 (0.36) ALDH1A1L3MBTL1CYP11B1HCRTR1HCRTR2
SCHEMBL22564457 0.81 SLC6A3 (0.34) GPBAR1KCNK3KCNK9ALDH1A1L3MBTL1
SCHEMBL22590927 0.81 KCNK3 (0.32) GPBAR1KCNK3KCNK9ALDH1A1L3MBTL1
SCHEMBL22563908 0.80 IRAK4 (0.41) GPBAR1KCNK3KCNK9ALDH1A1
SCHEMBL22564058 0.79 NOTUM (0.34) GPBAR1SCN9AGAA
SCHEMBL22564095 0.78 L3MBTL1 (0.32) ALDH1A1L3MBTL1
SCHEMBL22563802 0.77 TDP1 (0.35) ALDH1A1L3MBTL1GAA
SCHEMBL22564432 0.75 MYC (0.34) ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed