Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564531 | 0.91 | SGMS2 (0.38) | SGMS2NR1H4HTTKDM4EALDH1A1 | |
| SCHEMBL22564176 | 0.91 | HDAC3 (0.41) | SGMS2NR1H4HTTKDM4EALDH1A1 | |
| SCHEMBL22563927 | 0.88 | NR1H4 (0.38) | SGMS2NR1H4ALDH1A1TDP1KMT2A | |
| SCHEMBL18504406 | 0.87 | SGMS2 (0.39) | SGMS2NR1H4HTTKDM4EALDH1A1 | |
| SCHEMBL22564164 | 0.87 | ALDH1A1 (0.33) | NR1H4KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL22564462 | 0.87 | NR1H4 (0.42) | SGMS2NR1H4HTTALDH1A1TDP1 | |
| SCHEMBL22563912 | 0.87 | NR1H4 (0.37) | SGMS2NR1H4ALDH1A1ITGB1ITGA4 | |
| SCHEMBL22563974 | 0.86 | SGMS2 (0.38) | SGMS2NR1H4HTTHPGDPOLB | |
| SCHEMBL22564068 | 0.86 | SGMS2 (0.35) | SGMS2HTTALDH1A1HPGDTDP1 | |
| SCHEMBL22564186 | 0.86 | KMT2A (0.40) | SGMS2NR1H4HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |