Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564316 | 0.92 | KCNK3 (0.35) | KCNK3KCNK9IRAK4IDO1TDO2 | |
| SCHEMBL22563959 | 0.91 | KCNK3 (0.36) | KCNK3KCNK9IRAK4IDO1TDO2 | |
| SCHEMBL22564099 | 0.90 | ALDH1A1 (0.35) | LIG1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL18505061 | 0.88 | KCNK3 (0.35) | KCNK3KCNK9IRAK4IDO1TDO2 | |
| SCHEMBL22564503 | 0.88 | IRAK4 (0.35) | IRAK4IDO1TDO2ALDH1A1ACHE | |
| SCHEMBL22564195 | 0.88 | ALDH1A1 (0.35) | KCNK3KCNK9IRAK4IDO1TDO2 | |
| SCHEMBL22564283 | 0.88 | NR1H4 (0.38) | KCNK3KCNK9IRAK4IDO1TDO2 | |
| SCHEMBL22564309 | 0.88 | NPC1 (0.37) | LIG1RXFP1HDAC4HDAC1HDAC8 | |
| SCHEMBL22564196 | 0.87 | HCRTR1 (0.39) | KCNK3KCNK9LIG1ALDH1A1RXFP1 | |
| SCHEMBL22564143 | 0.87 | IRAK4 (0.47) | IRAK4IDO1TDO2BRPF1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |