Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | LMNA | P02545 | 7/20 | 0.35 |
| ▸ | HTT | P42858 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564292 | 0.91 | SMN1; SMN2 (0.36) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL22564541 | 0.90 | KCNK3 (0.35) | ALDH1A1LMNAMAPTTDP1LIG1 | |
| SCHEMBL18504470 | 0.88 | SMN1; SMN2 (0.35) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL22563858 | 0.88 | TAS2R14 (0.35) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL22563951 | 0.88 | KLKB1 (0.36) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL22564311 | 0.87 | LIG1 (0.35) | LIG1NPC1HDAC6 | |
| SCHEMBL22564535 | 0.87 | ROCK2 (0.34) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL22564366 | 0.87 | SMN1; SMN2 (0.34) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL22564309 | 0.86 | NPC1 (0.37) | LMNASMN1; SMN2LIG1NPC1RAB9A | |
| SCHEMBL22564308 | 0.85 | HDAC6 (0.39) | LMNALIG1KDM4EP2RX7HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |