Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26752289 | 0.88 | KDM4C (0.41) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL24458184 | 0.87 | CA1 (0.44) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL22564647 | 0.85 | EPHX2 (0.53) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL4320985 | 0.83 | ALDH1A1 (0.38) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL24458133 | 0.83 | CA1 (0.41) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL12608289 | 0.83 | ALDH1A1 (0.38) | CA1ALDH1A1TP53CHRNB2CHRNB4 | |
| SCHEMBL12156637 | 0.83 | ALDH1A1 (0.35) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL26742525 | 0.82 | CA1 (0.35) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL12209818 | 0.80 | ALDH1A1 (0.42) | KDM4CEPHX2CNR1ALDH1A1TP53 | |
| SCHEMBL21288117 | 0.79 | KDM4C (0.51) | KDM4CKDM4APHF8KDM2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |