SCHEMBL22566492

SCHEMBL22566492

C=C(C)C(=O)OCCc1ccc(CCc2ccc(CCc3ccc(CCOC(=O)C(=C)C)cc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.53
TSHR P16473 4/20 0.47
TDP1 Q9NUW8 2/20 0.46
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 1/20 0.41
CA1 P00915 3/20 0.40
CA2 P00918 2/20 0.40
THRA P10827 1/20 0.40
TYR P14679 1/20 0.39
CA12 O43570 1/20 0.39
MET P08581 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11921516 0.98 THRB (0.55) THRBTSHRTDP1POLBAPEX1
SCHEMBL27973892 0.93 HCAR2 (0.49) THRBTSHRTDP1POLBAPEX1
SCHEMBL10457799 0.93 THRB (0.50) THRBTSHRTDP1POLBAPEX1
SCHEMBL1119186 0.91 NPC1 (0.51) THRBTSHRTDP1POLBAPEX1
SCHEMBL13221752 0.91 THRB (0.49) THRBTSHRTDP1POLBAPEX1
SCHEMBL296203 0.91 CA1 (0.49) THRBTSHRTDP1POLBAPEX1
SCHEMBL147451 0.91 THRB (0.53) THRBTSHRTDP1POLBAPEX1
SCHEMBL2602558 0.90 THRB (0.49) THRBTSHRTDP1POLBAPEX1
SCHEMBL148596 0.90 THRB (0.47) THRBTSHRTDP1POLBAPEX1
SCHEMBL21112020 0.90 THRB (0.47) THRBTSHRTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-11773327-B2 PSA-type liquid crystal composition and display device having same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-03 US disclosed
US-20200332195-A1 PSA-TYPE LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE HAVING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-10-22 US disclosed