Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11921516 | 0.93 | THRB (0.55) | THRBTSHRALDH1A1THRAPOLB | |
| SCHEMBL22566492 | 0.91 | THRB (0.53) | THRBTSHRALDH1A1THRAPOLB | |
| SCHEMBL27637385 | 0.90 | TSHR (0.57) | THRBTSHRALDH1A1THRAPOLB | |
| SCHEMBL10457799 | 0.88 | THRB (0.50) | THRBTSHRALDH1A1THRAPOLB | |
| SCHEMBL2154214 | 0.87 | ALDH1A1 (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL14981546 | 0.87 | THRB (0.50) | THRBTSHRALDH1A1THRAPOLB | |
| SCHEMBL2602535 | 0.86 | THRB (0.43) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL13783931 | 0.86 | THRB (0.46) | THRBTSHRALDH1A1THRAPOLB | |
| SCHEMBL296203 | 0.86 | CA1 (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL13221752 | 0.86 | THRB (0.49) | THRBTSHRTHRAPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12492275-B2 | Photo-curable compositions containing high refractive index monomers for use in 3D printing applications | ARKEMA FRANCE (FR) | 2025-12-09 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4522665-A1 | RADIATION INDUCED RADICAL CURING BY SEMICONDUCTING NANOPARTICLES | Yeda Research and Development Co. Ltd (IL) | 2025-03-19 | — | — | EP | claimed |
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| US-20240142665-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| US-20240052081-A1 | PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS | ARKEMA FRANCE (FR) | 2024-02-15 | — | — | US | claimed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | claimed |
| EP-1177227-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2002-02-06 | — | — | EP | claimed |
| US-20020007032-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2002-01-17 | — | — | US | claimed |
| US-20010056165-A1 | Water plasticized high refractive index polymer for ophthalmic applications | SURGIDEV CORPORATION (US) | 2001-12-27 | — | — | US | claimed |
| US-6281319-B1 | HYDRATABLE POLYMER | SURGIDEV CORPORATION | 2001-08-28 | — | — | US | claimed |
| EP-1080382-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | Alcon Laboratories, Inc. (US) | 2001-03-07 | — | — | EP | claimed |
| WO-2000061646-A1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORPORATION (US) | 2000-10-19 | — | — | WO | claimed |
| US-6001128-A | CROSSLINKED ACRYLATED ESTER | ALCON LABORATORIES, INC. (US) | 1999-12-14 | — | — | US | claimed |
| WO-1999053347-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| EP-0914169-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1999-05-12 | — | — | EP | claimed |
| WO-1998053862-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1998-12-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | THRB 2506/4885TSHR 1437/4885ALDH1A1 1323/4885 |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | THRB 4655/4885TSHR 4604/4885ALDH1A1 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.