Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22559632 | 0.99 | KHK (0.66) | KHKNPC1RAB9AKDM4EHTT | |
| Hydrochloric Acid SCHEMBL29397092 | 0.99 | KHK (0.66) | KHKNPC1RAB9AKDM4EHTT | |
| SCHEMBL24851437 | 0.83 | KHK (0.63) | KHKNPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL22559658 | 0.83 | KHK (0.54) | KHKNPC1RAB9AKDM4EHTT | |
| SCHEMBL29369074 | 0.83 | KHK (0.54) | KHKNPC1RAB9AKDM4EHTT | |
| SCHEMBL23711726 | 0.82 | KHK (0.77) | KHKNPC1RAB9AKDM4EHTT | |
| SCHEMBL31279295 | 0.82 | KHK (0.77) | KHKNPC1RAB9AKDM4EHTT | |
| SCHEMBL22559642 | 0.81 | KHK (0.65) | KHKNPC1RAB9AKDM4EHTT | |
| SCHEMBL29369336 | 0.81 | KHK (0.65) | KHKNPC1RAB9AKDM4EHTT | |
| SCHEMBL23711780 | 0.81 | KHK (1.00) | KHKNPC1RAB9AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020215022-A1 | NOVEL COMPOUNDS AND METHODS OF USE TREATING FRUCTOSE-RELATED DISORDERS OR DISEASES | COLORADO RESEARCH PARTNERS, LLC (US) | 2020-10-22 | — | — | WO | disclosed |