Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23142821 | 0.87 | TP53 (0.51) | LMNATP53CYP17A1CA12CA1 | |
| SCHEMBL594716 | 0.87 | CYP17A1 (0.52) | CYP17A1CA12CA1CA2CA9 | |
| SCHEMBL3335259 | 0.87 | FAAH (0.62) | FAAH | |
| SCHEMBL13637520 | 0.87 | FAAH (0.62) | FAAHRAB9AALDH1A1TSHRMAPT | |
| SCHEMBL29730607 | 0.85 | CYP17A1 (0.48) | LMNATP53CYP17A1CA12CA1 | |
| SCHEMBL13827423 | 0.85 | CYP17A1 (0.48) | LMNATP53CYP17A1CA12CA1 | |
| SCHEMBL22006732 | 0.85 | APP (0.52) | LMNATP53CYP17A1CA12CA1 | |
| SCHEMBL15731128 | 0.85 | APP (0.52) | LMNATP53CYP17A1CA12CA1 | |
| SCHEMBL13306489 | 0.84 | CA1 (0.66) | CYP17A1CA12CA1CA2CA9 | |
| SCHEMBL1422634 | 0.84 | FAAH (0.49) | CYP17A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11111230-B2 | Indoleamine 2,3-dioxygenase inhibitors and use of same in medicine | ADLAI NORTYE BIOPHARMA CO., LTD. (CN) | 2021-09-07 | — | — | US | disclosed |
| US-20200331887-A1 | INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND USE OF SAME IN MEDICINE | XIAMEN BIOTIME BIOTECHNOLOGY CO., LTD. (CN) | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331887-A1 | INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS AND USE OF SAME IN MEDICINE | IDO1, IDO2, INMT | LMNA 4446/4885TP53 4413/4885CYP17A1 52/4885 |
| US-11111230-B2 | Indoleamine 2,3-dioxygenase inhibitors and use of same in medicine | IDO1, IDO2, INMT | LMNA 4446/4885TP53 4413/4885CYP17A1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.