SCHEMBL225707

SCHEMBL225707

COC(=O)C1CC2CC1C1C3C=CC(C3)C21

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM3 P20309 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
PKM P14618 1/20 0.31
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30209962 0.84 ALDH1A1 (0.34) CYP1A2HSD17B10SMN1; SMN2CYP2C19
SCHEMBL14510434 0.84 SMN1; SMN2 (0.36) SMN1; SMN2
SCHEMBL30209998 0.83
SCHEMBL4976985 0.83 MAPK1 (0.31) MAPK1
SCHEMBL12491194 0.83 ALDH1A1 (0.35) CYP1A2CYP3A4CYP2C19
SCHEMBL23254047 0.83 KDM4E (0.39) CYP1A2HSD17B10CYP3A4CYP2D6TSHR
SCHEMBL29325980 0.82 TSHR (0.30) TSHR
SCHEMBL13390627 0.81
SCHEMBL14494530 0.80 ALDH1A1 (0.36)
SCHEMBL30209984 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025087320-A1 OPTICAL MATERIAL 杭州睿丰融创科技有限公司 2025-05-01 WO claimed
CN-119431746-A Cycloolefin polymer hydride, resin composition, resin molded body and medical packaging material 杭州睿丰融创科技有限公司 2025-02-14 CN claimed
CN-117624555-A Optical material 杭州睿丰融创科技有限公司 2024-03-01 CN claimed
CN-112646126-B Method for preparing cycloolefin polymer by hydrogenation ring-opening metathesis polymerization method 益丰新材料股份有限公司 2023-03-07 CN claimed
EP-0850966-B1 Process for the preparation of hydrogenated ring opening metathese polymers BAYER AG (DE) 2000-09-13 EP claimed
EP-0850966-A1 Process for the preparation of hydrogenated ring opening metathese polymers BAYER AG (DE) 1998-07-01 EP claimed
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US claimed
EP-4737513-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737516-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737515-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737517-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4692228-A1 RESIN COMPOSITION AND MOLDED BODY Zeon Corporation (JP) 2026-02-11 EP disclosed
EP-4682199-A1 MEMBER, AND SEMICONDUCTOR MANUFACTURING?RELATED DEVICE Daikin Industries, Ltd. (JP) 2026-01-21 EP disclosed
US-5063096-A Norbornene polymer substrates; containing metallic oxide or fluoride NIPPON ZEON CO., LTD. (JP) 1991-11-05 US disclosed
EP-0451858-A2 Molded article of norbornene-based polymer NIPPON ZEON CO., LTD. (JP) 1991-10-16 EP disclosed
EP-0436372-A2 Thermoplastic materials and article made therefrom NIPPON ZEON CO., LTD. (JP) 1991-07-10 EP disclosed
EP-0405843-A2 Molding material NIPPON ZEON CO., LTD. (JP) 1991-01-02 EP disclosed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US disclosed
US-4176220-A COORDINATION CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1979-11-27 US disclosed
US-4039491-A IMPACT STRENGTH, NORBORNENE DERIVATIVE CONTAINING POLAR GROUP JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-08-02 US disclosed