SCHEMBL22574457

SCHEMBL22574457

N=C(Cl)c1nsc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ HSD17B10 Q99714 1/20 0.47
▸ TP53 P04637 8/20 0.42
▸ SMN1; SMN2 Q16637 3/20 0.42
▸ EPAS1 Q99814 3/20 0.41
▸ POLB P06746 1/20 0.39
▸ LMNA P02545 3/20 0.37
▸ RXFP1 Q9HBX9 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3995672 0.81 MAPT (0.57) MAPTKDM4EALDH1A1HSD17B10TP53
SCHEMBL591887 0.81 MAPT (0.49) MAPTKDM4EALDH1A1HSD17B10TP53
SCHEMBL27676968 0.76 TP53 (0.51) MAPTKDM4EALDH1A1HSD17B10TP53
SCHEMBL260433 0.74 MAPT (0.52) MAPTKDM4EALDH1A1HSD17B10TP53
SCHEMBL10436279 0.74 TP53 (0.50) MAPTKDM4EALDH1A1HSD17B10TP53
SCHEMBL7462724 0.74 MAPT (0.48) MAPTKDM4EALDH1A1HSD17B10TP53
SCHEMBL24897837 0.73 TP53 (0.52) MAPTKDM4EALDH1A1HSD17B10TP53
SCHEMBL1572476 0.73 MAPT (0.52) MAPTKDM4EALDH1A1HSD17B10TP53
Hydrochloric Acid SCHEMBL9036432 0.73 MAPT (0.51) MAPTKDM4EALDH1A1HSD17B10TP53
SCHEMBL5515080 0.72 TP53 (0.48) MAPTKDM4EALDH1A1HSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3728199-B1 PESTICIDAL COMPOUNDS BASF SE (DE) 2025-05-14 — — EP disclosed
CN-111491925-B Pesticidal compounds 巴斯夫欧洲公司 2023-12-29 — — CN disclosed
US-11512054-B2 Pesticidal compounds BASF SE (DE) 2022-11-29 — — US disclosed
US-20210070713-A1 PESTICIDAL COMPOUNDS BASF SE (DE) 2021-03-11 — — US disclosed
EP-3728199-A1 PESTICIDAL COMPOUNDS BASF SE (DE) 2020-10-28 — — EP disclosed
CN-111491925-A Pesticidal compounds 巴斯夫欧洲公司 2020-08-04 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210070713-A1 PESTICIDAL COMPOUNDS CAT, NIT2, PNMT MAPT 82/4885KDM4E 3608/4885ALDH1A1 1368/4885
US-11512054-B2 Pesticidal compounds CAT, NIT2, PNMT MAPT 82/4885KDM4E 3608/4885ALDH1A1 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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