Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676968 | 0.82 | TP53 (0.51) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10436279 | 0.81 | TP53 (0.50) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9036432 | 0.79 | MAPT (0.51) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL591887 | 0.79 | MAPT (0.49) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1572476 | 0.79 | MAPT (0.52) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL24897837 | 0.79 | TP53 (0.52) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL19142574 | 0.79 | TP53 (0.61) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7454304 | 0.76 | TP53 (0.57) | TP53MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL9038453 | 0.75 | TP53 (0.72) | TP53MAPTSMN1; SMN2POLBLMNA | |
| SCHEMBL4109025 | 0.75 | TP53 (0.50) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235352-B2 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2007-06-26 | — | — | US | disclosed |
| US-20070117054-A1 | Photothermographic material | FUJI PHOTO FILM CO., LTD. | 2007-05-24 | — | — | US | disclosed |
| US-20040018458-A1 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2004-01-29 | — | — | US | disclosed |
| US-20040005522-A1 | Photothermographic material | FUJIFILM CORPORATION (JP) | 2004-01-08 | — | — | US | disclosed |