Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12361543 | 0.83 | RAB9A (0.51) | TGFBR1TRPV1POLBTSHR | |
| SCHEMBL2257314 | 0.82 | TGFBR1 (0.47) | TGFBR1ALDH1A1RXRANR1H2NR1H3 | |
| SCHEMBL3225749 | 0.82 | TGFBR1 (0.47) | TGFBR1ALDH1A1SLC16A3SLC16A1RXRA | |
| SCHEMBL2254229 | 0.82 | KCNJ6 (0.49) | TGFBR1P2RY1POLB | |
| SCHEMBL2258904 | 0.81 | P2RY1 (0.51) | TGFBR1ALDH1A1KDM4ETRPV1CASP3 | |
| SCHEMBL2258277 | 0.81 | GLA (0.48) | TGFBR1ALDH1A1KDM4ETRPV1TSHR | |
| SCHEMBL12361506 | 0.81 | TGFBR1 (0.49) | TGFBR1ALDH1A1SLC16A3SLC16A1RXRA | |
| SCHEMBL2260793 | 0.81 | TGFBR1 (0.44) | TGFBR1ALDH1A1RXRANR1H2NR1H3 | |
| SCHEMBL2255891 | 0.81 | TGFBR1 (0.45) | TGFBR1ALDH1A1RXRANR1H2NR1H3 | |
| SCHEMBL15706879 | 0.81 | RAB9A (0.49) | TGFBR1ALDH1A1TRPV1P2RY1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998995-B2 | LXR and FXR modulators | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |