Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2261719 | 1.00 | CYP1A2 (0.41) | CYP1A2F3HPGDLMNAALDH1A1 | |
| SCHEMBL11480321 | 0.98 | CYP1A2 (0.40) | CYP1A2F3HPGDLMNAALDH1A1 | |
| SCHEMBL11480324 | 0.98 | CYP1A2 (0.40) | CYP1A2F3HPGDLMNAALDH1A1 | |
| SCHEMBL27510350 | 0.94 | CYP1A2 (0.42) | CYP1A2F3HPGDLMNAALDH1A1 | |
| SCHEMBL11266128 | 0.81 | NPC1 (0.44) | HTTMAOAMAPTNPC1RAB9A | |
| SCHEMBL1890698 | 0.81 | CYP1A2 (0.44) | CYP1A2HPGDLMNAALDH1A1HTT | |
| SCHEMBL1885997 | 0.81 | HSD11B1 (0.44) | HPGDALDH1A1PIM1PIM2GAA | |
| SCHEMBL1890697 | 0.81 | CYP1A2 (0.44) | CYP1A2HPGDLMNAALDH1A1HTT | |
| SCHEMBL1885998 | 0.81 | HSD11B1 (0.44) | HPGDALDH1A1PIM1PIM2GAA | |
| SCHEMBL11266130 | 0.81 | NPC1 (0.44) | HTTMAOAMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6087829-A | — | — | None | — | — | JP | disclosed |
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | GENECODE (EE) | 2026-01-22 | — | — | US | disclosed |
| US-11420961-B2 | Heterocyclic compounds | HOFFMANN-LA ROCHE INC. (US) | 2022-08-23 | — | — | US | disclosed |
| CN-111825654-A | Phenylmethylene piperidine derivatives, preparation method, intermediates and uses thereof | 北京酷瓴生物技术有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-111825654-A | Phenylmethylene piperidine derivatives, preparation method, intermediates and uses thereof | 北京酷瓴生物技术有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-111825654-A | Phenylmethylene piperidine derivatives, preparation method, intermediates and uses thereof | 北京酷瓴生物技术有限公司 | 2020-10-27 | — | — | CN | disclosed |
| WO-2018216823-A1 | ALPHA-AMINO AMIDE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-29 | — | — | WO | disclosed |
| US-8008326-B2 | 4-benzyledene-piperidin derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2011-08-30 | — | — | US | disclosed |
| CN-101580492-A | Method for preparing antiseptic triaryl-2-pyrazoline derivative by microwave | UNIV ZHEJIANG (CN) | 2009-11-18 | — | — | CN | disclosed |
| US-20080312222-A1 | 4-Benzyledene-Piperidin Derivatives | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-12-18 | — | — | US | disclosed |
| US-6166033-A | 2-carbonylthiazole derivatives and use of the same | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| WO-2000066559-A1 | PIPERIDINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS | SCHERING CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
| CN-1237971-A | 2-carbonylthiazole derivatives and use of the same | TAISHO PHARMACEUTICAL CO LTD (JP) | 1999-12-08 | — | — | CN | disclosed |
| EP-0940401-A1 | 2-CARBONYLTHIAZOLE DERIVATIVES AND USE OF THE SAME | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1999-09-08 | — | — | EP | disclosed |
| WO-1999034802-A1 | USE OF PHENYLTHIENYLMETHYLENE PIPERIDINE DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF DEPRESSION | AKZO NOBEL N.V. (NL) | 1999-07-15 | — | — | WO | disclosed |
| WO-1999034800-A1 | USE OF PHENYLTHIENYLMETHYLENE PIPERIDINE DERIVATIVE IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF MOVEMENT DISORDERS | AKZO NOBEL N.V. (NL) | 1999-07-15 | — | — | WO | disclosed |
| CN-1184478-A | Thiazole derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 1998-06-10 | — | — | CN | disclosed |
| CN-1090849-A | Arylidene-1-azacycloparaffin and aralkyl-1-azacycloparaffin, their salt contains medicament and the application and their preparation process of these compounds | THOMAE GMBH DR K (DE) | 1994-08-17 | — | — | CN | disclosed |
| JP-H0687829-A | BENZYLIDENEPIPERIDDINE DERIVATIVE | KANEGAFUCHI CHEM IND CO LTD | 1994-03-29 | — | — | JP | disclosed |
| US-4012392-A | ANALGESICS, MORPHINE ANTAGONISTS | ACF CHEMIEFARMA N.V. (NL) | 1977-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312222-A1 | 4-Benzyledene-Piperidin Derivatives | GRIN2C, GRIN2A, GRIN1 | CYP1A2 1192/4885F3 4716/4885HPGD 801/4885 |
| US-20260022096-A1 | NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS | CNR1, CDR2, SMN1; SMN2 | CYP1A2 2433/4885F3 2796/4885HPGD 2805/4885 |
| US-11420961-B2 | Heterocyclic compounds | LPXN, MLX, CCNY | CYP1A2 10/4885F3 108/4885HPGD 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.