Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.72 |
| ▸ | RECQL | P46063 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.72 |
| ▸ | USP2 | O75604 | 6/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | HBB | P68871 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 10/20 | 0.65 |
| ▸ | BLM | P54132 | 9/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | CASP1 | P29466 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | S100A4 | P26447 | 6/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.58 |
| ▸ | MMP2 | P08253 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30714406 | 1.00 | MEN1 (0.72) | MEN1KMT2ARECQLMAPTSMN1; SMN2 | |
| SCHEMBL2136732 | 1.00 | MEN1 (0.72) | MEN1KMT2ARECQLMAPTSMN1; SMN2 | |
| SCHEMBL14214095 | 0.89 | MEN1 (0.85) | MEN1KMT2ARECQLMAPTSMN1; SMN2 | |
| SCHEMBL30864532 | 0.88 | PTGS1 (0.65) | MEN1KMT2ARECQLMAPTSMN1; SMN2 | |
| Iremycin SCHEMBL30003721 | 0.87 | MEN1 (0.61) | MEN1KMT2ARECQLMAPTSMN1; SMN2 | |
| Rodorubicin SCHEMBL8693 | 0.87 | MEN1 (0.58) | MEN1KMT2ARECQLMAPTSMN1; SMN2 | |
| Rodorubicin SCHEMBL29352818 | 0.87 | MEN1 (0.58) | MEN1KMT2ARECQLMAPTSMN1; SMN2 | |
| SCHEMBL18593715 | 0.85 | MEN1 (0.62) | MEN1KMT2ARECQLMAPTSMN1; SMN2 | |
| SCHEMBL29711323 | 0.85 | MEN1 (0.63) | MEN1KMT2ARECQLMAPTSMN1; SMN2 | |
| Cosmomycin C SCHEMBL30610383 | 0.85 | PTGS1 (0.62) | MEN1KMT2ARECQLMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220196660-A1 | Methods for Modulation of Acetyltransferase Activity and Applications Thereof Including Treatments | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-06-23 | — | — | US | disclosed |
| WO-2020219598-A1 | METHODS FOR MODULATION OF ACETYLTRANSFERASE ACTIVITY AND APPLICATIONS THEREOF INCLUDING TREATMENTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-10-29 | — | — | WO | disclosed |