Rodorubicin

Rodorubicin

SCHEMBL8693

CC[C@@]1(O)C[C@H](O[C@H]2C[C@H](N(C)C)[C@H](O[C@H]3C[C@@H]4O[C@H]5CC(=O)[C@H](C)O[C@H]5O[C@@H]4[C@H](C)O3)[C@H](C)O2)c2c(O)c3c(c(O)c2[C@H]1O[C@H]1C[C@H](N(C)C)[C@H](O)[C@H](C)O1)C(=O)c1cccc(O)c1C3=O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.58
KMT2A Q03164 11/20 0.58
RECQL P46063 8/20 0.58
MAPT P10636 7/20 0.58
SMN1; SMN2 Q16637 7/20 0.58
USP2 O75604 6/20 0.58
CYP3A4 P08684 5/20 0.58
TP53 P04637 2/20 0.58
HBB P68871 1/20 0.58
PTGS1 P23219 3/20 0.56
MMP2 P08253 3/20 0.56
HTR2B P41595 2/20 0.56
THRB P10828 10/20 0.54
BLM P54132 9/20 0.54
KDM4E B2RXH2 4/20 0.54
CASP1 P29466 2/20 0.54
HSD17B10 Q99714 2/20 0.54
S100A4 P26447 6/20 0.47
PAX8 Q06710 5/20 0.47
HSP90AA1 P07900 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rodorubicin SCHEMBL29352818 1.00 MEN1 (0.58) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL30504362 0.97 PTGS1 (0.56) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29403905 0.95 PTGS1 (0.54) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29356967 0.92 PTGS1 (0.57) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29557045 0.92 MMP2 (0.58) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29884381 0.92 PTGS1 (0.67) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29381144 0.88 PTGS1 (0.50) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL2136732 0.87 MEN1 (0.72) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL22589699 0.87 MEN1 (0.72) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL30714406 0.87 MEN1 (0.72) MEN1KMT2ARECQLMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 22656 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
EP-4743490-A1 HUMANIZED ANTI-CD7 ANTIBODY Christian-Albrechts-Universität zu Kiel (DE) 2026-05-20 EP claimed
WO-2026099502-A1 NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2026-05-15 WO claimed
US-20260115305-A1 LINKERS, CONJUGATES AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE SUZHOU CO LTD (CN) 2026-04-30 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-20260085100-A1 METHODS OF ANTIGEN PRODUCTION THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) 2026-03-26 US claimed
US-20260077056-A1 LINKER-PAYLOAD COMPOUND, CONJUGATES AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE SUZHOU CO LTD (CN) 2026-03-19 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4698185-A1 METHODS AND SYSTEMS FOR IMPROVING ANTI-CANCER THERAPIES Osasuna Therapeutics SA (CH) 2026-02-25 EP claimed
EP-4694935-A1 COMBINATION OF ANTIBODY-DRUG CONJUGATE AND ANTI-PD-1 ANTIBODY, AND USE THEREOF Genequantum Healthcare (Suzhou) Co., Ltd. (CN) 2026-02-18 EP claimed
CN-1616099-A Anti-cancer medicine composition KONG QINGZHONG (CN) 2005-05-18 CN claimed
EP-1286692-A4 INTRATHECAL ADMINISTRATION OF RITUXIMAB FOR TREATMENT OF CENTRAL NERVOUS SYSTEM LYMPHOMAS IDEC PHARMA CORP (US) 2004-11-17 EP claimed
WO-2004050057-A2 AN EXOPOLYSACCHARIDES DELIVERY SYSTEM FOR ACTIVE MOLECULES TECHNOLOGIES BIOLACTIS INC. (CA) 2004-06-17 WO claimed
CN-1437478-A Intrathecal administration of rituximab for the treatment of central nervous system lymphomas IDEC PHARMA CORP (US) 2003-08-20 CN claimed
EP-1286692-A1 INTRATHECAL ADMINISTRATION OF RITUXIMAB FOR TREATMENT OF CENTRAL NERVOUS SYSTEM LYMPHOMAS Idec Pharmaceuticals Corporation (US) 2003-03-05 EP claimed
US-20020009444-A1 Intrathecal administration of rituximab for treatment of central nervous system lymphomas IDEC PHARMACEUTICALS CORPORATION (US) 2002-01-24 US claimed
WO-2001080884-A1 INTRATHECAL ADMINISTRATION OF RITUXIMAB FOR TREATMENT OF CENTRAL NERVOUS SYSTEM LYMPHOMAS IDEC PHARMACEUTICALS CORPORATION (US) 2001-11-01 WO claimed
EP-0393575-B1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent SEARLE & CO (US) 1994-03-16 EP claimed
EP-0393575-A1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent G.D. Searle & Co. (US) 1990-10-24 EP claimed
EP-0325113-A1 Stabilised dried preparation containing cytostatic anthracyclin antibiotics, and processes for preparing them HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-26 EP claimed