Rodorubicin

Rodorubicin

SCHEMBL29352818

CC[C@@]1(O)C[C@H](O[C@H]2C[C@H](N(C)C)[C@H](O[C@H]3C[C@@H]4O[C@H]5CC(=O)[C@H](C)O[C@H]5O[C@@H]4[C@H](C)O3)[C@H](C)O2)c2c(O)c3c(c(O)c2[C@H]1O[C@H]1C[C@H](N(C)C)[C@H](O)[C@H](C)O1)C(=O)c1cccc(O)c1C3=O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.58
KMT2A Q03164 11/20 0.58
RECQL P46063 8/20 0.58
MAPT P10636 7/20 0.58
SMN1; SMN2 Q16637 7/20 0.58
USP2 O75604 6/20 0.58
CYP3A4 P08684 5/20 0.58
TP53 P04637 2/20 0.58
HBB P68871 1/20 0.58
PTGS1 P23219 3/20 0.56
MMP2 P08253 3/20 0.56
HTR2B P41595 2/20 0.56
THRB P10828 10/20 0.54
BLM P54132 9/20 0.54
KDM4E B2RXH2 4/20 0.54
CASP1 P29466 2/20 0.54
HSD17B10 Q99714 2/20 0.54
S100A4 P26447 6/20 0.47
PAX8 Q06710 5/20 0.47
HSP90AA1 P07900 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rodorubicin SCHEMBL8693 1.00 MEN1 (0.58) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL30504362 0.97 PTGS1 (0.56) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29403905 0.95 PTGS1 (0.54) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29356967 0.92 PTGS1 (0.57) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29557045 0.92 MMP2 (0.58) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29884381 0.92 PTGS1 (0.67) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL29381144 0.88 PTGS1 (0.50) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL2136732 0.87 MEN1 (0.72) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL22589699 0.87 MEN1 (0.72) MEN1KMT2ARECQLMAPTSMN1; SMN2
SCHEMBL30714406 0.87 MEN1 (0.72) MEN1KMT2ARECQLMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
CN-119367549-A Hydrophilic linkers and conjugates thereof 芬兰吉利科斯有限公司 2025-01-28 CN claimed
WO-2024240173-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2024-11-28 WO claimed
EP-3541414-B1 CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODS OBI PHARMA INC (TW) 2024-08-28 EP claimed
CN-118251241-A Antibodies, linkers, supports, conjugates and uses thereof 启德医药科技(苏州)有限公司 2024-06-25 CN claimed
EP-3380124-B1 CONJUGATES COMPRISING SELF-IMMOLATIVE GROUPS AND METHODS RELATED THERETO LEGOCHEM BIOSCIENCES INC (KR) 2024-04-03 EP claimed
EP-3122757-B1 CHARGED LINKERS AND THEIR USES FOR CONJUGATION HANGZHOU DAC BIOTECH CO LTD (CN) 2023-09-06 EP claimed
EP-3641824-B1 HYDROPHILIC LINKERS AND CONJUGATES THEREOF GLYKOS FINLAND OY (FI) 2022-08-31 EP claimed
EP-3218007-B1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CANCER INST NAT SANTE RECH MED (FR) 2022-04-06 EP claimed
WO-2026107389-A1 CHROMATIN LANDSCAPES AND CELL-FREE DNA FRAGMENTATION FOR COLORECTAL CANCER DETECTION THE JOHNS HOPKINS UNIVERSITY (US) 2026-05-21 WO disclosed
CN-117024411-B Isoquinoline as HPK1 inhibitor 豪夫迈·罗氏有限公司 2026-05-19 CN disclosed
CN-122028918-A TRIM7 inhibitors and uses thereof 沙塔克实验室有限公司 2026-05-12 CN disclosed
CN-122005761-A Methods of treating diseases and conditions using interleukin-10 阿尔莫生物科技股份有限公司 2026-05-12 CN disclosed
CN-120202022-A Cell targeting constructs and uses thereof 研究发展基金会 2025-06-24 CN disclosed
CN-114031689-A Bispecific anti-human CD 20/human transferrin receptor antibodies and methods of use 豪夫迈·罗氏有限公司 2022-02-11 CN disclosed
CN-114014936-A Bispecific anti-human CD 20/human transferrin receptor antibodies and methods of use 豪夫迈·罗氏有限公司 2022-02-08 CN disclosed
CN-114026106-A Abiraterone prodrugs 普洛拉治疗公司 2022-02-08 CN disclosed
CN-113967194-A Subcutaneous anti-HER 2 antibody formulation 霍夫曼-拉罗奇有限公司 2022-01-25 CN disclosed
CN-113966344-A anti-BCMA antibody conjugates, compositions comprising the same, and methods of making and using the same 细胞基因公司 2022-01-21 CN disclosed
CN-113956358-A anti-TIGIT antibodies and methods of use 豪夫迈·罗氏有限公司 2022-01-21 CN disclosed