Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 8/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | HTT | P42858 | 7/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22589718 | 0.85 | ADCY1 (0.78) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589752 | 0.85 | ADCY1 (0.69) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589868 | 0.83 | KCNK2 (0.47) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589730 | 0.83 | ADCY1 (0.74) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL20597939 | 0.82 | ADCY1 (1.00) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589706 | 0.82 | ADCY1 (0.67) | ADCY1KDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL22589774 | 0.82 | KDM4E (0.58) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL20598288 | 0.82 | ADCY1 (1.00) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589707 | 0.81 | ADCY1 (0.74) | ADCY1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL22589750 | 0.81 | ADCY1 (0.62) | ADCY1KDM4ELMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220249447-A1 | CF3-, OCF3-, SCF3-, and SF5-Containing Antibacterial Agents | PURDUE RESEARCH FOUNDATION | 2022-08-11 | — | — | US | disclosed |
| EP-3958679-A1 | CF3-, OCF3-, SCF3- AND SF5-CONTAINING ANTIBACTERIAL AGENTS | Purdue Research Foundation (US) | 2022-03-02 | — | — | EP | disclosed |
| WO-2020219792-A1 | CF3-, OCF3-, SCF3- AND SF5-CONTAINING ANTIBACTERIAL AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2020-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220249447-A1 | CF3-, OCF3-, SCF3-, and SF5-Containing Antibacterial Agents | SFXN3, CCR3, SF3A3 | ADCY1 4672/4885KDM4E 2632/4885MEN1 4209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.