Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20017064 | 0.76 | KCNH2 (0.43) | ALDH1A1 | |
| SCHEMBL24198949 | 0.76 | GCGR (0.32) | ALDH1A1 | |
| SCHEMBL14418806 | 0.74 | — | — | |
| SCHEMBL13384633 | 0.73 | KMT2A (0.44) | NPSR1ALDH1A1 | |
| SCHEMBL4633204 | 0.69 | NPC1 (0.48) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL21419520 | 0.69 | HTT (0.39) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL21959175 | 0.67 | TYR (0.34) | — | |
| SCHEMBL22213081 | 0.67 | — | — | |
| SCHEMBL21131900 | 0.66 | GPR35 (0.31) | — | |
| SCHEMBL4824479 | 0.65 | HTT (0.37) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815256-B2 | Dithiophene compound, preparation and its application in organic photovoltaics thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815256-B2 | Dithiophene compound, preparation and its application in organic photovoltaics thereof | DDT, TST, DIMT1 | NPC1 4777/4885HPGD 2316/4885MAPK1 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.