Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 4/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19397177 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL12120873 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL15910828 | 0.79 | ADA (0.56) | SMN1; SMN2ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL29070737 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL13672555 | 0.76 | SMN1; SMN2 (0.40) | SMN1; SMN2ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL9925251 | 0.76 | L3MBTL1 (0.43) | SMN1; SMN2ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL19910566 | 0.76 | ADA (0.41) | SMN1; SMN2ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL19848258 | 0.76 | DDB1 (0.41) | DHODHALDH1A1MAPK14KDM4E | |
| SCHEMBL29435809 | 0.76 | DDB1 (0.41) | DHODHALDH1A1MAPK14KDM4E | |
| SCHEMBL7032810 | 0.75 | L3MBTL1 (0.41) | SMN1; SMN2ADORA2AADORA2BADORA1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673893-B2 | CDK inhibitors and their use as pharmaceuticals | PRELUDE THERAPEUTICS INCORPORATED (US) | 2023-06-13 | — | — | US | claimed |
| US-20260078114-A1 | COMPOUND USED AS INHIBITOR OF CDK4 KINASE AND USE THEREOF | TYK MEDICINES INC (CN) | 2026-03-19 | — | — | US | disclosed |
| US-12378232-B2 | Cyclin dependent kinase inhibitors | PFIZER INC. (US) | 2025-08-05 | — | — | US | disclosed |
| US-20230144528-A1 | CDK Inhibitors And Their Use As Pharmaceuticals | PRELUDE THERAPEUTICS, INCORPORATED | 2023-05-11 | — | — | US | disclosed |
| US-20220089580-A1 | CYCLIN DEPENDENT KINASE INHIBITORS | PFIZER INC. (US) | 2022-03-24 | — | — | US | disclosed |
| US-20200339543-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339543-A1 | AGRICULTURAL CHEMICALS | ABAT, BRDT, GABBR1 | SMN1; SMN2 4739/4885DHODH 385/4885ADORA2A 4064/4885 |
| US-11673893-B2 | CDK inhibitors and their use as pharmaceuticals | CDK6, CDK3, CDK9 | SMN1; SMN2 1821/4885DHODH 1747/4885ADORA2A 2839/4885 |
| US-20230144528-A1 | CDK Inhibitors And Their Use As Pharmaceuticals | CDK6, CDK3, CDK9 | SMN1; SMN2 1821/4885DHODH 1747/4885ADORA2A 2839/4885 |
| US-20260078114-A1 | COMPOUND USED AS INHIBITOR OF CDK4 KINASE AND USE THEREOF | CDK4, CDK1, CDK3 | SMN1; SMN2 2035/4885DHODH 3405/4885ADORA2A 3621/4885 |
| US-12378232-B2 | Cyclin dependent kinase inhibitors | CCNY, CCNI, CCNK | SMN1; SMN2 4086/4885DHODH 3991/4885ADORA2A 3985/4885 |
| US-20220089580-A1 | CYCLIN DEPENDENT KINASE INHIBITORS | CCNY, CCNI, CCNK | SMN1; SMN2 4086/4885DHODH 3991/4885ADORA2A 3985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.