Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.40 |
| ▸ | METAP2 | P50579 | 9/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069186 | 0.79 | BRD4 (0.37) | BRD4METAP2ALDH1A1KDM4EHPGD | |
| SCHEMBL22600407 | 0.76 | HSP90AA1 (0.36) | BRD4METAP2ALDH1A1KDM4EHPGD | |
| SCHEMBL25300623 | 0.72 | BRD4 (0.51) | BRD4METAP2 | |
| SCHEMBL22600098 | 0.71 | BRD4 (0.58) | BRD4 | |
| SCHEMBL31590048 | 0.70 | BRD4 (0.50) | BRD4METAP2 | |
| SCHEMBL31590019 | 0.68 | KMT2A (0.49) | BRD4METAP2MAPT | |
| SCHEMBL21227712 | 0.68 | BRD4 (0.59) | BRD4ALDH1A1KDM4EHPGD | |
| SCHEMBL31590022 | 0.68 | BRD4 (0.43) | BRD4METAP2 | |
| SCHEMBL21227677 | 0.67 | KDM4E (0.41) | BRD4METAP2MAPTKDM4E | |
| SCHEMBL28495832 | 0.67 | METAP2 (0.37) | BRD4METAP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3958867-B1 | SMALL MOLECULE BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE LLC (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2020219168-A1 | SMALL MOLECULE BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE, LLC (US) | 2020-10-29 | — | — | WO | disclosed |