Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 7/20 | 0.36 |
| ▸ | BRD4 | O60885 | 6/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22600170 | 0.76 | BRD4 (0.40) | METAP2BRD4ALDH1A1KDM4EHPGD | |
| SCHEMBL15069186 | 0.76 | BRD4 (0.37) | METAP2BRD4ALDH1A1KDM4EHPGD | |
| SCHEMBL21445298 | 0.73 | BRD4 (0.55) | BRD4 | |
| SCHEMBL12258192 | 0.71 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1METAP2ALDH1A1KDM4E | |
| SCHEMBL23589864 | 0.70 | BRD9 (0.43) | METAP2BRD4ALDH1A1KDM4EHPGD | |
| SCHEMBL29303306 | 0.70 | LMNA (0.39) | BRD4ALDH1A1HPGD | |
| SCHEMBL24556359 | 0.69 | BRD4 (0.43) | BRD4 | |
| SCHEMBL24556402 | 0.69 | BRD4 (0.44) | BRD4 | |
| SCHEMBL12563121 | 0.68 | BRD4 (0.55) | BRD4ALDH1A1 | |
| SCHEMBL19297126 | 0.68 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1METAP2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020219168-A1 | SMALL MOLECULE BROMODOMAIN INHIBITORS AND USES THEREOF | CONVERGENE, LLC (US) | 2020-10-29 | — | — | WO | disclosed |