Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360053 | 1.00 | TDP1 (0.49) | TDP1POLBHTTAPEX1MAPT | |
| SCHEMBL815901 | 0.97 | HTT (0.54) | TDP1POLBHTTAPEX1MAPT | |
| SCHEMBL803172 | 0.93 | TDP1 (0.56) | TDP1POLBHTTAPEX1MAPT | |
| SCHEMBL103219 | 0.93 | THRB (0.44) | TDP1HTTMAPTKMT2ATHRB | |
| SCHEMBL29365274 | 0.93 | THRB (0.44) | TDP1HTTMAPTKMT2ATHRB | |
| SCHEMBL19078821 | 0.92 | THRB (0.43) | TDP1POLBHTTAPEX1MAPT | |
| SCHEMBL17301280 | 0.92 | THRB (0.43) | TDP1HTTMAPTKMT2ATHRB | |
| SCHEMBL17070342 | 0.91 | MAPT (0.41) | TDP1POLBHTTAPEX1MAPT | |
| SCHEMBL14038295 | 0.91 | MAPT (0.41) | TDP1POLBHTTAPEX1MAPT | |
| SCHEMBL14088544 | 0.91 | HTT (0.43) | TDP1POLBHTTAPEX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339884-A1 | LIQUID CRYSTAL COMPOSITION AND USE THEREOF | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2020-10-29 | — | — | US | disclosed |