Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22600354 | 1.00 | ELANE (0.41) | ELANETHRBKMT2AATMAPP | |
| SCHEMBL22600351 | 0.95 | ELANE (0.41) | ELANETHRBKMT2AATMAPP | |
| SCHEMBL22600350 | 0.95 | ELANE (0.41) | ELANETHRBKMT2AATMAPP | |
| SCHEMBL18194819 | 0.94 | ELANE (0.42) | ELANETHRBKMT2AATMAPP | |
| SCHEMBL18194796 | 0.94 | ELANE (0.42) | ELANETHRBKMT2AATMAPP | |
| SCHEMBL9607895 | 0.92 | ELANE (0.47) | ELANEKMT2AATMAPPCYP2C19 | |
| SCHEMBL9607896 | 0.89 | THRB (0.43) | THRBAPPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL14984702 | 0.89 | ELANE (0.35) | ELANETHRBKMT2AATMAPP | |
| SCHEMBL14984722 | 0.89 | ELANE (0.35) | ELANETHRBKMT2AATMAPP | |
| SCHEMBL18966013 | 0.88 | LMNA (0.45) | THRBKMT2AAPPCYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339884-A1 | LIQUID CRYSTAL COMPOSITION AND USE THEREOF | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2020-10-29 | — | — | US | disclosed |