Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 7/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.35 |
| ▸ | ITGAV | P06756 | 8/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.33 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.32 |
| ▸ | OXGR1 | Q96P68 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21282934 | 1.00 | SUCNR1 (0.35) | SUCNR1ITGB3ITGAVITGB6ITGB1 | |
| SCHEMBL21282932 | 0.87 | GRM2 (0.32) | JMJD6OXTRFGFR1FGFR2FGFR4 | |
| SCHEMBL21282937 | 0.86 | MTNR1A (0.34) | ITGB3ITGAVITGB6ITGB1ITGA5 | |
| SCHEMBL21282930 | 0.86 | MAPT (0.37) | ITGB3ITGAVITGB6JMJD6OXTR | |
| SCHEMBL21311521 | 0.83 | ITGB3 (0.38) | SUCNR1ITGB3ITGAVITGB6ITGB1 | |
| SCHEMBL20153874 | 0.82 | JMJD6 (0.33) | ITGB3ITGAVITGB6JMJD6OXTR | |
| SCHEMBL20153311 | 0.81 | ITGB3 (0.36) | SUCNR1ITGB3ITGAVITGB6ITGB1 | |
| SCHEMBL23677937 | 0.80 | JMJD6 (0.36) | ITGB3ITGAVITGB6JMJD6OXTR | |
| SCHEMBL20140487 | 0.80 | ITGB3 (0.39) | SUCNR1ITGB3ITGAVITGB6ITGB1 | |
| SCHEMBL23462844 | 0.79 | ITGAV (0.40) | SUCNR1ITGB3ITGAVITGB6ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11028071-B2 | Indazole derivatives as alpha v integrin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200339540-A1 | INDAZOLE DERIVATIVES AS ALPHA V INTEGRIN ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339540-A1 | INDAZOLE DERIVATIVES AS ALPHA V INTEGRIN ANTAGONISTS | ITGAV, ITGB1, ITGB3 | SUCNR1 2603/4885ITGB3 3/4885ITGAV 1/4885 |
| US-11028071-B2 | Indazole derivatives as alpha v integrin antagonists | ITGAV, ITGB1, ITGB3 | SUCNR1 2603/4885ITGB3 3/4885ITGAV 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.