Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 6/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22587808 | 0.90 | PTGER4 (0.46) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL22601043 | 0.87 | PTGER4 (0.48) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL24313791 | 0.85 | KDM4E (0.51) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL31723074 | 0.85 | KDM4E (0.51) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL22588427 | 0.84 | BCAT1 (0.43) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL24313739 | 0.84 | HDAC6 (0.41) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL31723075 | 0.84 | HDAC6 (0.41) | NPC1RAB9ASMN1; SMN2TP53MEN1 | |
| SCHEMBL30538408 | 0.84 | BCAT1 (0.55) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL22588433 | 0.83 | BCAT1 (0.48) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL24313562 | 0.83 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3959202-B1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AG (DE) | 2023-08-16 | — | — | EP | claimed |
| EP-3959202-B1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AG (DE) | 2023-08-16 | — | — | EP | disclosed |
| WO-2020216701-A1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | WO | disclosed |