Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22587808 | 0.89 | PTGER4 (0.46) | PTGER4MMP2MMP14KDM4EMEN1 | |
| SCHEMBL22601136 | 0.87 | NPC1 (0.49) | PTGER4MMP2MMP14KDM4EMEN1 | |
| SCHEMBL24313791 | 0.84 | KDM4E (0.51) | PTGER4KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL31723074 | 0.84 | KDM4E (0.51) | PTGER4KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL31723093 | 0.84 | TAS1R3 (0.42) | PTGER4MMP2MEN1NPC1ALDH1A1 | |
| SCHEMBL24313815 | 0.84 | TAS1R3 (0.42) | PTGER4MMP2MEN1NPC1ALDH1A1 | |
| SCHEMBL22588190 | 0.83 | MAPT (0.48) | PTGER4KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL22588102 | 0.83 | GAA (0.46) | PTGER4KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL22588427 | 0.83 | BCAT1 (0.43) | PTGER4MMP2MMP14KDM4EMEN1 | |
| SCHEMBL30538408 | 0.83 | BCAT1 (0.55) | MMP2MMP14KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3959202-B1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AG (DE) | 2023-08-16 | — | — | EP | claimed |
| CN-114072394-A | Acylsulfonamides for the treatment of cancer | 拜耳股份公司 | 2022-02-18 | — | — | CN | claimed |
| EP-3959202-B1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AG (DE) | 2023-08-16 | — | — | EP | disclosed |
| CN-114072394-A | Acylsulfonamides for the treatment of cancer | 拜耳股份公司 | 2022-02-18 | — | — | CN | disclosed |
| WO-2020216701-A1 | ACYL SULFONAMIDES FOR TREATING CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | WO | disclosed |