SCHEMBL22601378

SCHEMBL22601378

Cc1cnn2c(N)n[nH]c(=O)c12

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31034907 0.79
SCHEMBL24500013 0.72 HCAR2 (0.34)
SCHEMBL22601396 0.69 CDK8 (0.34)
SCHEMBL21353952 0.62 CYP1A2 (0.35)
SCHEMBL19533293 0.61 JAK1 (0.36) LMNATSHR
SCHEMBL25607547 0.60 DAO (0.33)
SCHEMBL23122140 0.60 ALDH1A1 (0.41) LMNA
SCHEMBL22601397 0.59 KDM4E (0.34) TSHR
SCHEMBL12157513 0.59
SCHEMBL31386674 0.59 DYRK1A (0.39) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020216327-A1 DERIVATIVES OF GLYCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) 2020-10-29 WO disclosed