Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363648 | 0.76 | CDK2 (0.45) | MEN1KMT2AHSP90AA1 | |
| SCHEMBL22601380 | 0.76 | CDK2 (0.34) | MAPK1 | |
| SCHEMBL18520805 | 0.72 | KDM4E (0.41) | KDM4EHTTMEN1NPC1KMT2A | |
| SCHEMBL21754187 | 0.69 | CYP11B2 (0.39) | KDM4EMEN1NPC1KMT2ASMN1; SMN2 | |
| SCHEMBL4301939 | 0.68 | KDM4E (0.32) | KDM4EHTTMEN1NPC1KMT2A | |
| SCHEMBL18520806 | 0.67 | FABP6 (0.37) | HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL10407271 | 0.63 | KDM4E (0.41) | KDM4EHTTMEN1NPC1KMT2A | |
| SCHEMBL13650606 | 0.63 | ALDH1A1 (0.44) | KDM4EHTTMEN1NPC1KMT2A | |
| SCHEMBL13650607 | 0.63 | KDM4E (0.34) | KDM4EHTTNPC1KMT2AMAPT | |
| SCHEMBL24225927 | 0.62 | KDM5A (0.50) | KDM4EHTTKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216327-A1 | DERIVATIVES OF GLYCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2020-10-29 | — | — | WO | disclosed |