Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19662730 | 0.82 | HSD17B3 (0.48) | HSD17B3MAPK1MEN1KMT2ATSHR | |
| SCHEMBL27271336 | 0.79 | ALDH1A1 (0.47) | CHRM2HTR1AADRA2ACHRM1DRD2 | |
| SCHEMBL20139342 | 0.76 | KDM4E (0.47) | HTR1ADRD2HTR2ASLC6A4HRH1 | |
| SCHEMBL20139341 | 0.76 | KDM4E (0.47) | HTR1ADRD2HTR2ASLC6A4HRH1 | |
| SCHEMBL27090004 | 0.75 | HDAC3 (0.46) | HTR1ADRD2PTGS1HSD17B3MAPK1 | |
| SCHEMBL10760089 | 0.74 | CHRM2 (0.38) | CHRM2HTR1AADRA2ACHRM1DRD2 | |
| SCHEMBL23883100 | 0.74 | HDAC3 (0.48) | HTR1ADRD2PTGS1SLC6A3MEN1 | |
| SCHEMBL25698882 | 0.74 | HDAC3 (0.45) | CHRM2CHRM1OPRM1HSD17B3MEN1 | |
| SCHEMBL23883102 | 0.74 | HDAC3 (0.48) | HTR1ADRD2PTGS1SLC6A3MEN1 | |
| SCHEMBL25699276 | 0.73 | SLC6A2 (0.52) | CHRM2CHRM1DRD2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216607-A1 | LABELING OF A PROTEIN OR A POLYPEPTIDE | ETH ZURICH (CH) | 2020-10-29 | — | — | WO | disclosed |