Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 18/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | THPO | P40225 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27271336 | 0.80 | ALDH1A1 (0.47) | SLC6A2SLC6A4SLC6A3CHRM2CYP2D6 | |
| Mezepine SCHEMBL38660320 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A4CYP3A4SLC6A3CHRM2 | |
| Mezepine SCHEMBL2110147 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A4CYP3A4SLC6A3CHRM2 | |
| SCHEMBL25697533 | 0.79 | HDAC3 (0.51) | DRD2LMNAMTNR1AMTNR1B | |
| SCHEMBL25698882 | 0.77 | HDAC3 (0.45) | CHRM2CHRM1CHRM3MEN1KMT2A | |
| SCHEMBL8199134 | 0.77 | SLC6A2 (0.63) | SLC6A2SLC6A4CYP3A4SLC6A3CHRM2 | |
| SCHEMBL19662730 | 0.77 | HSD17B3 (0.48) | MAPK1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL20139341 | 0.76 | KDM4E (0.47) | SLC6A4DRD2HTR2AHRH1DRD3 | |
| SCHEMBL20139342 | 0.76 | KDM4E (0.47) | SLC6A4DRD2HTR2AHRH1DRD3 | |
| SCHEMBL27090004 | 0.75 | HDAC3 (0.46) | DRD2MAPK1SCN5AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107415-A1 | COMPOSITIONS COMPRISING MODIFIED PHOSPHOLIPIDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-06-15 | — | — | WO | disclosed |