Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.51 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22601451 | 0.98 | HRH4 (0.54) | HRH4CHKAHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL20224121 | 0.86 | HRH4 (0.56) | HRH4HSD17B10LMNASMN1; SMN2MEN1 | |
| SCHEMBL20224125 | 0.85 | LMNA (0.45) | HSD17B10LMNASMN1; SMN2PIK3CDPIK3CA | |
| SCHEMBL20224122 | 0.85 | ADRB2 (0.51) | HRH4ALDH1A1 | |
| SCHEMBL22601526 | 0.82 | CHRNA7 (0.47) | HRH4HSD17B10LMNASMN1; SMN2MEN1 | |
| SCHEMBL22601438 | 0.82 | KDM4E (0.45) | HRH4HSD17B10LMNASMN1; SMN2MEN1 | |
| SCHEMBL22601446 | 0.81 | MEN1 (0.43) | HRH4HSD17B10LMNASMN1; SMN2MEN1 | |
| SCHEMBL24008771 | 0.81 | HRH4 (0.50) | HRH4CHKAHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL22601437 | 0.80 | LMNA (0.49) | HSD17B10LMNASMN1; SMN2MEN1MAPT | |
| SCHEMBL22601449 | 0.80 | HSD17B10 (0.55) | HSD17B10LMNASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339530-A1 | UREA DERIVATIVES AS INHIBITORS OF ASK1 | HEPAGENE THERAPEUTICS, INC. (VG) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339530-A1 | UREA DERIVATIVES AS INHIBITORS OF ASK1 | ATF1, ERN1, MAP3K1 | HRH4 4032/4885CHKA 899/4885HSD17B10 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.