Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22602099 | 0.85 | FKBP1A (0.39) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28225824 | 0.84 | FKBP1A (0.40) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL16749487 | 0.82 | FKBP1A (0.41) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL16749275 | 0.82 | FKBP1A (0.41) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL17924716 | 0.82 | FKBP1A (0.41) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL16541366 | 0.77 | PEPD (0.39) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL16800201 | 0.77 | PEPD (0.39) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL16800190 | 0.77 | PEPD (0.39) | FKBP1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL22601986 | 0.76 | MEN1 (0.44) | FKBP1AMEN1KMT2ATSHRKDM4E | |
| SCHEMBL1269177 | 0.76 | FKBP1A (0.38) | FKBP1AMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216766-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC INTERNATIONAL GMBH (DE) | 2020-10-29 | — | — | WO | disclosed |