SCHEMBL226039

SCHEMBL226039

COC(C)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHCY P23526 10/20 0.63
ADORA2B P29275 4/20 0.61
ADORA3 P0DMS8 3/20 0.61
DOT1L Q8TEK3 2/20 0.60
ADORA2A P29274 2/20 0.60
DPP4 P27487 1/20 0.60
MEN1 O00255 1/20 0.60
SLC28A1 O00337 1/20 0.60
MAP3K7 O43318 1/20 0.60
SLC28A2 O43868 1/20 0.60
GAPDH P04406 1/20 0.60
MAPK1 P28482 1/20 0.60
ADORA1 P30542 1/20 0.60
STAT6 P42226 1/20 0.60
PI4KA P42356 1/20 0.60
KMT2A Q03164 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
PI4K2B Q8TCG2 1/20 0.60
SLC29A1 Q99808 1/20 0.60
PI4K2A Q9BTU6 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15643454 0.88 PRMT5 (0.63) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL2403046 0.87 PRMT5 (0.52) AHCYADORA2BADORA3DOT1LHSP90B1
SCHEMBL17460352 0.87 PRMT5 (0.54) AHCYADORA2BADORA3DOT1L
SCHEMBL22326785 0.87 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL18520788 0.87 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL29352139 0.87 AHCY (0.63) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL16300875 0.87 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL22326787 0.87 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL21413837 0.87 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A
SCHEMBL13173634 0.87 PRMT5 (0.64) AHCYADORA2BADORA3DOT1LADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120064427-A Method and analysis system for detecting brain nucleic acid hydrolysate spatial distribution based on mass spectrum imaging 北京脑科学与类脑研究所 2025-05-30 CN claimed
EP-4384635-A1 IN SITU EPITRANSCRIPTOMIC PROFILING The Broad Institute Inc. (US) 2024-06-19 EP claimed
WO-2024086659-A2 COMPOSITION AND METHODS FOR DETECTING ADENINE MODIFICATIONS THE UNIVERSITY OF CHICAGO (US) 2024-04-25 WO claimed
US-20240011084-A1 METHODS FOR FULL-LENGTH REVERSE TRANSCRIPTION PCR OF LONG RNAs CONTAINING MODIFIED RIBONUCLEOSIDES USING A THERMOSTABLE REVERSE TRANSCRIPTASE NORTHWESTERN UNIVERSITY 2024-01-11 US claimed
CN-116298235-A Serum metabolism biomarker for diagnosing or monitoring breast cancer and screening method thereof 哈尔滨医科大学 2023-06-23 CN claimed
CN-115943307-A MR1 ligands and pharmaceutical compositions for immunomodulation 巴塞尔大学 2023-04-07 CN claimed
US-20230099822-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION UNIVERSITÄT BASEL (CH) 2023-03-30 US claimed
WO-2023023055-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-02-23 WO claimed
WO-2023018756-A1 IN SITU EPITRANSCRIPTOMIC PROFILING THE BROAD INSTITUTE, INC. (US) 2023-02-16 WO claimed
CN-114076805-B Method for enriching methylated adenosine in urine and application thereof 浙江大学 2022-07-26 CN claimed
WO-2022115822-A2 METHODS FOR FULL-LENGTH REVERSE TRANSCRIPTION PCR OF LONG RNAS CONTAINING MODIFIED RIBONUCLEOSIDES USING A THERMOSTABLE REVERSE TRANSCRIPTASE NORTHWESTERN UNIVERSITY (US) 2022-06-02 WO claimed
CN-114076805-A Method for enriching methylated adenosine in urine and application thereof 浙江大学 2022-02-22 CN claimed
WO-2021144475-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION UNIVERSITÄT BASEL (CH) 2021-07-22 WO claimed
CN-104804903-B Semiconductor cleaning agent with metal line 恩特格里斯公司 2018-10-30 CN claimed
CN-106399506-A Diagnostic methods for determining prognosis of non-small cell lung cancer 雅培分子公司 2017-02-15 CN claimed
EP-2755986-A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF Moderna Therapeutics, Inc. (US) 2014-07-23 EP claimed
WO-2013039857-A1 ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF modeRNA Therapeutics (US) 2013-03-21 WO claimed
WO-2001085220-A1 LABELED NUCLEOSIDES AND METHOD FOR THEIR PREPARATION RNA-TEC N.V. (BE) 2001-11-15 WO claimed
JP-57145898-A None JP disclosed
JP-S57145898-A NOVEL N6, N6-DIMETHYLADENOSINE DERIVATIVE ARAKAWA CHIYOUTAROU KK 1982-09-09 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230099822-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION MRGPRX1, MRGPRX2, CD47 AHCY 2480/4885ADORA2B 133/4885ADORA3 77/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.