Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22604303 | 1.00 | CACNA1I (0.47) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL22587370 | 0.79 | TRPA1 (0.44) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL22604310 | 0.79 | TRPA1 (0.44) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL2593288 | 0.78 | B3GNT2 (0.45) | CACNA1ITRPA1KMT2AMAPTTSHR | |
| SCHEMBL1693739 | 0.78 | NR1I2 (0.46) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL29815050 | 0.78 | B3GNT2 (0.45) | CACNA1ITRPA1KMT2AMAPTTSHR | |
| SCHEMBL12069878 | 0.78 | NR1I2 (0.46) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL16088895 | 0.78 | B3GNT2 (0.45) | CACNA1ITRPA1KMT2AMAPTTSHR | |
| SCHEMBL31187827 | 0.76 | PDE2A (0.52) | CACNA1ICACNA1GCACNA1HCNR2KCNH2 | |
| SCHEMBL22604311 | 0.76 | CA12 (0.40) | CNR2ITGB3ITGA2BSUCNR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267309-A1 | DIMERIC OR POLYMERIC FORM OF MUTANT IDH INHIBITOR | Epitas Biosciences (shanghai) Co., Ltd. (CN) | 2022-08-25 | — | — | US | disclosed |
| EP-3964508-A1 | DIMERIC OR POLYMERIC FORM OF MUTANT IDH INHIBITOR | Epitas Biosciences (Shanghai) Co., Ltd. (CN) | 2022-03-09 | — | — | EP | disclosed |
| WO-2020216071-A1 | DIMERIC OR POLYMERIC FORM OF MUTANT IDH INHIBITOR | 上海仕谱生物科技有限公司 | 2020-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267309-A1 | DIMERIC OR POLYMERIC FORM OF MUTANT IDH INHIBITOR | IDH3B, IDH1, IDH3A | CACNA1I 3063/4885CACNA1G 3805/4885CACNA1H 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.