Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.62 |
| ▸ | CTSL | P07711 | 4/20 | 0.60 |
| ▸ | ACE | P12821 | 4/20 | 0.60 |
| ▸ | CTSS | P25774 | 2/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.55 |
| ▸ | CTSV | O60911 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 3/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.54 |
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27679107 | 0.96 | CTSL (0.64) | CA2PTPN1CTSLACECTSS | |
| SCHEMBL4359915 | 0.96 | CTSL (0.64) | CA2PTPN1CTSLACECTSS | |
| SCHEMBL4369316 | 0.95 | CTSL (0.63) | CA2PTPN1CTSLACECTSS | |
| SCHEMBL4357736 | 0.92 | ACE (0.68) | CA2PTPN1CTSLACECTSS | |
| SCHEMBL4356229 | 0.92 | ACE (0.68) | CA2PTPN1CTSLACECTSS | |
| SCHEMBL1305154 | 0.90 | PTPN1 (0.70) | CA2PTPN1CTSLACECA1 | |
| SCHEMBL8510030 | 0.90 | PTPN1 (0.70) | CA2PTPN1CTSLACECA1 | |
| SCHEMBL28760302 | 0.88 | CTSL (0.67) | CA2PTPN1CTSLACECTSS | |
| SCHEMBL4369236 | 0.88 | CTSL (0.67) | CA2PTPN1CTSLACECTSS | |
| SCHEMBL13669589 | 0.88 | CTSL (0.67) | CA2PTPN1CTSLACECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216240-A1 | DICYCLIC ALKANE COMPOUND USEFUL AS INHIBITOR OF PLASMA KALLIKREIN | 南京明德新药研发有限公司 | 2020-10-29 | — | — | WO | disclosed |