Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22588324 | 0.85 | KDM1A (0.45) | PANK3L3MBTL1KDM1AKDM4EGAA | |
| SCHEMBL31285938 | 0.85 | KDM1A (0.45) | PANK3L3MBTL1KDM1AKDM4EGAA | |
| SCHEMBL28527704 | 0.83 | MAPK1 (0.53) | HRH3PANK3KDM4EMAPTPOLB | |
| SCHEMBL22588174 | 0.83 | MLNR (0.53) | HRH3KDM1APOLBMLNR | |
| SCHEMBL31285937 | 0.83 | MLNR (0.53) | HRH3KDM1APOLBMLNR | |
| SCHEMBL22605517 | 0.78 | HDAC3 (0.60) | HRH3HDAC2HDAC1 | |
| SCHEMBL31285852 | 0.78 | HDAC3 (0.60) | HRH3HDAC2HDAC1 | |
| SCHEMBL16407626 | 0.76 | MAPT (0.55) | KDM4EGAAMAPTHDAC2HDAC1 | |
| SCHEMBL3991264 | 0.74 | KDM4E (0.57) | KDM1AKDM4EGAAMAPTHDAC2 | |
| SCHEMBL27927411 | 0.74 | L3MBTL1 (0.55) | L3MBTL1KDM4EPOLBALDH1A1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-B | Heterocyclic compound, application thereof and composition containing same | 健艾仕生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |