Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 12/20 | 0.56 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | MLNR | O43193 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.50 |
| ▸ | ME1 | P48163 | 1/20 | 0.50 |
| ▸ | ME3 | Q16798 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | PHGDH | O43175 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22605614 | 0.89 | DRD2 (0.58) | SIGMAR1PHGDH | |
| SCHEMBL22605589 | 0.81 | MLNR (0.54) | SYKMLNRHRH3ME2ME1 | |
| SCHEMBL31285937 | 0.80 | MLNR (0.53) | SYKMLNRHRH3ME2ME1 | |
| SCHEMBL22588174 | 0.80 | MLNR (0.53) | SYKMLNRHRH3ME2ME1 | |
| SCHEMBL22605908 | 0.79 | HRH3 (0.58) | MLNRHRH3ME2ME1ME3 | |
| SCHEMBL22587771 | 0.79 | MLNR (0.52) | SYKMLNRHRH3ME2ME1 | |
| SCHEMBL22588179 | 0.79 | MLNR (0.54) | SYKMLNRHRH3ME2ME1 | |
| SCHEMBL31285860 | 0.79 | MLNR (0.54) | SYKMLNRHRH3ME2ME1 | |
| SCHEMBL22587995 | 0.78 | HRH3 (0.45) | HRH3ME2ME1ME3 | |
| SCHEMBL22587877 | 0.77 | MAPK1 (0.56) | MLNRHRH3ME2ME1ME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-B | Heterocyclic compound, application thereof and composition containing same | 健艾仕生物医药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| WO-2020216378-A1 | HETEROCYCLIC COMPOUND, APPLICATION THEREOF, AND COMPOSITION CONTAINING SAME | 健艾仕生物医药有限公司 | 2020-10-29 | — | — | WO | disclosed |