Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22606455 | 1.00 | MEN1 (0.43) | MEN1KMT2AEPHX2TSHRRECQL | |
| SCHEMBL22802989 | 1.00 | MEN1 (0.43) | MEN1KMT2AEPHX2TSHRRECQL | |
| SCHEMBL20327715 | 0.98 | EPHX2 (0.43) | MEN1KMT2AEPHX2TSHRRECQL | |
| SCHEMBL8537710 | 0.92 | MEN1 (0.48) | MEN1KMT2ATSHRRECQLHPGD | |
| SCHEMBL8537552 | 0.92 | MEN1 (0.48) | MEN1KMT2ATSHRRECQLHPGD | |
| SCHEMBL8536337 | 0.90 | TSHR (0.45) | MEN1KMT2ATSHRRECQLHPGD | |
| SCHEMBL26252508 | 0.89 | TSHR (0.41) | MEN1KMT2AEPHX2TSHRRECQL | |
| SCHEMBL24508454 | 0.89 | MEN1 (0.47) | MEN1KMT2ATSHRRECQLHPGD | |
| SCHEMBL22856422 | 0.89 | ALDH1A1 (0.47) | MEN1KMT2AEPHX2TSHRHPGD | |
| SCHEMBL15888695 | 0.89 | ALDH1A1 (0.47) | MEN1KMT2AEPHX2TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020219650-A1 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 12 (CDK12) AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-10-29 | — | — | WO | disclosed |