Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17286874 | 0.87 | KDM4E (0.77) | KDM4EALDH1A1LMNAMAPTADORA2A | |
| SCHEMBL808191 | 0.87 | KDM4E (0.77) | KDM4EALDH1A1LMNAMAPTADORA2A | |
| SCHEMBL808420 | 0.87 | KDM4E (0.77) | KDM4EALDH1A1LMNAMAPTADORA2A | |
| SCHEMBL4087331 | 0.86 | KDM4E (0.75) | KDM4EALDH1A1LMNAMAPTADORA2A | |
| Hydrochloric Acid SCHEMBL5803147 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1LMNAMAPTADORA2A | |
| SCHEMBL6329397 | 0.83 | KDM4E (0.71) | KDM4EALDH1A1LMNAMAPTADORA2A | |
| SCHEMBL15860248 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1LMNAMAPTADORA2A | |
| SCHEMBL27711581 | 0.83 | KDM4E (0.71) | KDM4EALDH1A1LMNAMAPTADORA2A | |
| SCHEMBL29423640 | 0.83 | KDM4E (1.00) | KDM4EALDH1A1LMNAMAPTADORA2A | |
| SCHEMBL5803149 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1LMNAMAPTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11706982-B2 | Fused polycyclic compound, and preparation method and use thereof | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2023-07-18 | — | — | US | disclosed |
| US-20200343455-A1 | Fused Polycyclic Compound, and Preparation Method and Use Thereof | NINGBO LUMILAN ADVANCED MATERIALS, CO., LTD. (CN) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11706982-B2 | Fused polycyclic compound, and preparation method and use thereof | INF2, INTS9, PYM1 | KDM4E 2744/4885ALDH1A1 3407/4885LMNA 413/4885 |
| US-20200343455-A1 | Fused Polycyclic Compound, and Preparation Method and Use Thereof | INF2, INTS9, PYM1 | KDM4E 2744/4885ALDH1A1 3407/4885LMNA 413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.