Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 8/20 | 0.53 |
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22607141 | 0.94 | SOS1 (0.51) | SOS1BCHEACHEOPRM1OPRK1 | |
| SCHEMBL22607008 | 0.90 | BCHE (0.58) | SOS1BCHEACHECYP2D6 | |
| SCHEMBL22606965 | 0.90 | SOS1 (0.48) | SOS1BCHEACHE | |
| SCHEMBL22607143 | 0.90 | SOS1 (0.52) | SOS1BCHEACHECYP2D6OPRM1 | |
| SCHEMBL22606795 | 0.89 | SOS1 (0.48) | SOS1BCHEACHECYP2D6 | |
| SCHEMBL22606646 | 0.88 | SOS1 (0.54) | SOS1BCHEACHECYP2D6 | |
| SCHEMBL22606664 | 0.87 | BCHE (0.47) | BCHEACHECYP2D6 | |
| SCHEMBL22607010 | 0.86 | PTGS2 (0.49) | SOS1PTGS2 | |
| SCHEMBL22607014 | 0.84 | SOS1 (0.52) | SOS1BCHEACHEOPRM1OPRK1 | |
| SCHEMBL22606966 | 0.83 | BCHE (0.52) | SOS1BCHEACHECYP2D6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339537-A1 | NOVEL COMPOUND AS INHIBITOR AGAINST BINDING OF PF34 PROTEIN TO NEDD4-1 PROTEIN AND USE THEREOF | ENHANCEDBIO, INC. (KR) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339537-A1 | NOVEL COMPOUND AS INHIBITOR AGAINST BINDING OF PF34 PROTEIN TO NEDD4-1 PROTEIN AND USE THEREOF | NEDD4, PFDN1, PF4 | SOS1 1806/4885BCHE 4287/4885ACHE 3500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.