Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 10/20 | 0.46 |
| ▸ | DRD3 | P35462 | 9/20 | 0.46 |
| ▸ | DRD4 | P21917 | 8/20 | 0.44 |
| ▸ | HTR1A | P08908 | 7/20 | 0.44 |
| ▸ | DRD1 | P21728 | 7/20 | 0.44 |
| ▸ | DRD5 | P21918 | 7/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22609144 | 0.90 | EPHX1 (0.48) | L3MBTL1EPHX1HTR6ACHE | |
| SCHEMBL22609016 | 0.88 | EPHX1 (0.46) | L3MBTL1EPHX1HTR6DRD2ACHE | |
| SCHEMBL22608964 | 0.87 | MCHR1 (0.47) | L3MBTL1 | |
| SCHEMBL22609012 | 0.87 | EPHX1 (0.47) | L3MBTL1EPHX1HTR6ACHE | |
| SCHEMBL22619233 | 0.86 | EPHX1 (0.45) | L3MBTL1EPHX1HTR6DRD2ACHE | |
| SCHEMBL22609003 | 0.86 | EPHX1 (0.44) | L3MBTL1EPHX1HTR6DRD2ACHE | |
| SCHEMBL22608966 | 0.85 | L3MBTL1 (0.44) | L3MBTL1EPHX1DRD2ACHE | |
| SCHEMBL22619069 | 0.85 | L3MBTL1 (0.44) | L3MBTL1EPHX1HTR6DRD2ACHE | |
| SCHEMBL22619209 | 0.84 | L3MBTL1 (0.45) | L3MBTL1EPHX1HTR6ACHE | |
| SCHEMBL22608986 | 0.84 | L3MBTL1 (0.46) | L3MBTL1EPHX1HTR6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956931-B | Tetrahydropyrrole compound, preparation method thereof, pharmaceutical composition and application thereof | 迈第康(上海)生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |
| US-20210024498-A1 | TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | MEDICONNS SHANGHAI BIOPHARMACEUTICAL CO LTD (CN) | 2021-01-28 | — | — | US | disclosed |
| CN-111978294-A | Preparation method of tetrahydropyrrole compound | 迈第康(上海)生物医药科技有限公司 | 2020-11-24 | — | — | CN | disclosed |
| EP-3733670-A1 | TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | Mediconns (Shanghai) Biopharmaceutical Co., Ltd (CN) | 2020-11-04 | — | — | EP | disclosed |
| CN-109956931-A | Tetrahydropyrrole compound, preparation method, pharmaceutical composition and purposes | 迈第康(上海)生物医药科技有限公司 | 2019-07-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024498-A1 | TETRAHYDROPYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | PRLHR, DRD2, AVPR2 | L3MBTL1 3997/4885EPHX1 4138/4885HTR6 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.