SCHEMBL22609174

SCHEMBL22609174

CCCCC1(O)OC(=O)c2ccc(OC)cc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.48
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 1/20 0.42
PDK2 Q15119 4/20 0.40
CYP1A1 P04798 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 2/20 0.38
HRH3 Q9Y5N1 1/20 0.38
KDM4E B2RXH2 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
EDNRB P24530 1/20 0.37
EDNRA P25101 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23747878 0.83 CYP2C9 (0.40) CA1CA2CA4CA7CA9
SCHEMBL29502553 0.79 NPSR1 (0.49) PTPN1MEN1GAAKMT2ACYP2C9
SCHEMBL21325292 0.79 NPSR1 (0.49) PTPN1MEN1GAAKMT2ACYP2C9
SCHEMBL6271326 0.79 NPSR1 (0.49) PTPN1MEN1GAAKMT2ACYP2C9
SCHEMBL22609192 0.77 PTPN1 (0.56) PTPN1MEN1GAAKMT2AALDH1A1
SCHEMBL4028258 0.75 NPSR1 (0.49) MEN1GAAKMT2APDK2CYP2C9
SCHEMBL31094210 0.73 SLC5A1 (0.37) PTPN1CYP2C9CYP2C19SLC10A2
SCHEMBL11826749 0.72 PDK2 (0.47) CA1CA2CA4CA7CA9
SCHEMBL6101688 0.72 PGR (0.46) CA1CA2CA4CA7CA9
SCHEMBL3618729 0.71 EDNRA (0.52) CA1CA2CA4CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111819170-B Methods for synthesizing pulmonary clothing acids and analogs thereof 韩国海洋研究院 2023-12-29 CN disclosed
EP-3733656-B1 METHOD FOR SYNTHESIS OF LOBARIC ACID AND ANALOG THEREOF KOREA INSTITUTE OF OCEAN SCIENCE AND TECH (KR) 2023-05-10 EP disclosed
US-11434217-B2 Method for synthesis of lobaric acid and analog thereof KOREA INSTITUTE OF OCEAN SCIENCE AND TECHNOLOGY (KR) 2022-09-06 US disclosed
US-20210246112-A1 METHOD FOR SYNTHESIS OF LOBARIC ACID AND ANALOG THEREOF KOREA INSTITUTE OF OCEAN SCIENCE AND TECHNOLOGY (KR) 2021-08-12 US disclosed
EP-3733656-A1 METHOD FOR SYNTHESIS OF LOBARIC ACID AND ANALOG THEREOF Korea Institute of Ocean Science and Technology (KR) 2020-11-04 EP disclosed
CN-111819170-A Method for synthesizing pneumocandic acid and analogues thereof 韩国海洋研究院 2020-10-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246112-A1 METHOD FOR SYNTHESIS OF LOBARIC ACID AND ANALOG THEREOF PPP6C, PPP4C, PPP3CB PTPN1 129/4885CA1 1903/4885CA2 1072/4885
US-11434217-B2 Method for synthesis of lobaric acid and analog thereof PPP6C, PPP4C, PPP3CB PTPN1 129/4885CA1 1903/4885CA2 1072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.