⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29088611 | 0.77 | BRD4 (0.33) | — | |
| SCHEMBL30696846 | 0.72 | — | — | |
| SCHEMBL1905722 | 0.69 | GAA (0.41) | — | |
| SCHEMBL21047619 | 0.68 | LMNA (0.32) | — | |
| SCHEMBL31292622 | 0.67 | POLB (0.43) | — | |
| SCHEMBL21047706 | 0.67 | HSD17B10 (0.30) | — | |
| SCHEMBL9464929 | 0.67 | NOS1 (0.38) | — | |
| SCHEMBL21047857 | 0.65 | — | — | |
| SCHEMBL22609499 | 0.64 | CYP11B1 (0.33) | — | |
| SCHEMBL5967475 | 0.63 | SMPD3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250114345-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS | 2025-04-10 | — | — | US | disclosed |
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |