Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071086 | 1.00 | SIGMAR1 (0.49) | SIGMAR1DRD2IDO1KDM4EALDH1A1 | |
| SCHEMBL21071095 | 0.92 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1A | |
| SCHEMBL22609374 | 0.92 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1A | |
| SCHEMBL21071364 | 0.92 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1A | |
| SCHEMBL21070953 | 0.92 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1A | |
| SCHEMBL21071107 | 0.92 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1A | |
| SCHEMBL21070675 | 0.92 | IDO1 (0.47) | IDO1AKT1ADRB2HTR1A | |
| SCHEMBL21070267 | 0.90 | IDO1 (0.49) | SIGMAR1IDO1AKT1ADRB2HTR1A | |
| SCHEMBL22609552 | 0.89 | IDO1 (0.45) | SIGMAR1IDO1AKT1ADRB2HTR1A | |
| SCHEMBL21070300 | 0.84 | IDO1 (0.43) | SIGMAR1IDO1TDP1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |