Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21071021 | 1.00 | FPR3 (0.47) | FPR3FPR2ABHD6DAGLAKDM1A | |
| SCHEMBL6610814 | 0.89 | DAGLA (0.54) | ABHD6DAGLAKDM1APRMT5KMT2A | |
| SCHEMBL20129716 | 0.89 | DAGLA (0.54) | ABHD6DAGLAKDM1APRMT5KMT2A | |
| SCHEMBL21070281 | 0.87 | ABHD6 (0.42) | ABHD6DAGLAKDM1APRMT5KMT2A | |
| SCHEMBL12260685 | 0.85 | KLK7 (0.42) | FPR3FPR2ABHD6DAGLAKDM1A | |
| SCHEMBL4664791 | 0.85 | KLK7 (0.52) | ABHD6DAGLAKDM1APRMT5KMT2A | |
| SCHEMBL7908485 | 0.85 | KLK7 (0.52) | ABHD6DAGLAKDM1APRMT5KMT2A | |
| SCHEMBL7908488 | 0.85 | KLK7 (0.52) | ABHD6DAGLAKDM1APRMT5KMT2A | |
| SCHEMBL30428955 | 0.85 | DAGLA (0.48) | ABHD6DAGLAKDM1APRMT5KMT2A | |
| SCHEMBL12663132 | 0.83 | ALOX5AP (0.41) | FPR3FPR2ABHD6DAGLAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731869-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2020-11-04 | — | — | EP | disclosed |